Valvular & structural heart disease
End of Life After Transcatheter Aortic Valve Replacement: A Danish Nationwide Cohort Study
Authors' conclusion
End of life for TAVR patients is characterized by high frailty and comorbidity burden. Importantly, most hospitalizations are of noncardiovascular cause
Study context
- Population
- Deceased patients who underwent transcatheter aortic valve replacement (TAVR), Danish nationwide registers, 2008–2022median age 86 years, 55.1% males
- Participants
- 2,544 vs 25,440
- Exposure
- Deceased TAVR patients vs matched general-population controls
- TAVRn = 2,544
- Controlsn = 25,440reference
- Outcome
- Patient characteristics and hospitalizations at end of life
- Follow-up
- Last year of life
Methodological detailsnationwide registers, 1:10 matched on age, sex and calendar year of death
- Nationwide registers
- 1:10 matched on age, sex and calendar year of death
Main finding
As reported in the abstract
Hospitalization >28 days
Observational data: associations, not effects.
Further findings
Intermediate/high frailty
HF
CKD
Hospitalizations for noncardiovascular cause (of all hospitalizations) · last year of life
CV hospitalizations (of all hospitalizations) · last year of life
Hospitalizations for symptoms (of all hospitalizations) · last year of life
HF hospitalizations (of CV hospitalizations) · last year of life
- Hospitalizations for noncardiovascular cause (of all hospitalizations): of 6,943 vs 49,438 hospitalizations
Original publication
End of Life After Transcatheter Aortic Valve Replacement: A Danish Nationwide Cohort Study. JACC Cardiovasc Interv. Published 23 December 2024. doi:10.
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