Heart failure & cardiomyopathies
In-Hospital Observation on Oral Diuretics After Treatment for Acute Decompensated Heart Failure: Evaluating the Utility
Main finding · 30-day readmission, Yale cohortResult — go to the resultHazard ratio 0.98 95% CI 0.93–1.05Authors' conclusion
In-hospital OOD did not provide actionable information on diuretic response, was not associated with outpatient dose selection, did not predict subsequent outpatient diuretic response, and was not associated with lower readmission rate.
Study context
- Population
- Patients treated for acute decompensated HF (Mechanisms of Diuretic Resistance (MDR) cohort; Yale multicentre cohort)MDR cohort
- Participants
- 468 patients
- Exposure
- In-hospital observation on oral diuretics vs no on oral diuretics (OOD)
- OODn = 265
- Outcome
- Utility of in-hospital OOD
Main finding
30-day readmission, Yale cohort
Hazard ratio
0.98
95% CI 0.93–1.05
P = 0.51
OODvs No OOD
HR 0.98 (95% CI 0.93–1.05); P = 0.51
As reported in the abstract
- Weight change vs net fluid balance during OOD correlation
- r=0.36
- Discharge dose decreased from OOD dose by weight increased/stable/decreased
- 77% versus 72% versus 70%
- Discharge dose decreased from OOD dose by net fluid status
- 100% versus 69% versus 74%
- Discharge dose decreased from OOD dose by urine output
- 69% versus 79% versus 72%
- Discharge dosing similar across categories
- P > 0.27
- Outpatient vs inpatient OOD natriuresis correlation (n=98)
- r=0.26
Observational data: associations, not effects.
Original publication
In-Hospital Observation on Oral Diuretics After Treatment for Acute Decompensated Heart Failure: Evaluating the Utility. Circ Heart Fail. Published 10 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →