Heart failure & cardiomyopathies
Medication Adherence in Patients with Acutely Decompensated Heart Failure: A Cross-Sectional Study in the Emergency Department (ADHF-ED)
Authors' conclusion
Adherence to CHF medication in patients presenting with ADHF was low. Non-adherence represents a significant contributor to worsening CHF, potentially leading to ADHF hospitalization.
Study context
- Population
- Patients with acutely decompensated heart failure (ADHF) presenting in the ED
- Participants
- 100 patients
- Exposure
- Adherent vs Partially adherent vs Non-adherent
- Outcome
- Medication adherence by self-report and qualitative toxicological urine analysis
Methodological detailsemergency department
- Emergency department
Main finding
As reported in the abstract
Adherence to CHF medication (urine toxicology)
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Number of CHF medications prescribedNon-adherent vs Partially adherent · significantly higher in non-adherent | P = 0.0047 |
| Number of CHF medications prescribedNon-adherent vs Adherent · significantly higher in non-adherent | P = 0.0002 |
| Pill burdenNon-adherent vs Adherent · significantly higher in non-adherent | P = 0.002 |
| AgeNon-adherent vs Partially adherent · non-adherent younger | P = 0.0144 |
| AgeNon-adherent vs Adherent · non-adherent younger | P = 0.0054 |
Abnormal DemTect cognitive screening result
- Adherent patients significantly more likely to have an abnormal DemTect result
- P = 0.049
Third-party medication preparation
- Medication prepared by a third party (caregiver or pharmacist) reduced the likelihood of non- and partial adherence
Self-reported adherence
- Self-reported adherence monitoring inaccurate
Original publication
Medication Adherence in Patients with Acutely Decompensated Heart Failure: A Cross-Sectional Study in the Emergency Department (ADHF-ED). Eur J Heart Fail. Published 10 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →