Heart failure & cardiomyopathies
Patterns of diuretic titration during inpatient management of acute decompensated heart failure
Authors' conclusion
There was wide variation in diuretic strategies at a single academic medical center. Increased time to initial IV loop diuretic, time between diuretic doses, and longer time to max diuretic therapy were associated with increased LOS but were not associated with 30-day readmission
Study context
- Population
- Adults hospitalised for acute decompensated heart failure (ADHF) regardless of left ventricular ejection fraction (LVEF), quaternary healthcare system, 2014–2021
- Participants
- 4,298 adults
- Outcome
- Diuretic practice patterns; association of time to initial, second and maximum diuretic therapy with hospital LOS and 30-day readmission
Methodological detailssingle academic medical center
- Single academic medical center
Main finding
As reported in the abstract
Median time to max diuretic therapy
1.8 (0.7, 3.8) days
Median time to initial IV loop diuretic dose
3.6 (2.1, 6.5) hours
Time to second IV loop diuretic dose
10.2 (6.3, 15.1) hours
Observational data: associations, not effects.
Original publication
Patterns of diuretic titration during inpatient management of acute decompensated heart failure. Am Heart J. Published 27 December 2024. doi:10.
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