Coronary disease & ACS

Utility of cardiovascular magnetic resonance in patients with stable troponin elevation

Eur Heart J Cardiovasc ImagingPublished Retrospective cohort study

Authors' conclusion

CMR identified a cause for stable troponin elevation in 7 of 10 cases, and a new diagnosis was evident in 1 of 4 cases. CMR improved the net reclassification of patients with stable troponin elevation.

Study context

Population
Patients with cardiac chest pain/dyspnoea and stable troponin elevation undergoing cardiovascular magnetic resonance (CMR)
Participants
225 patients
Outcome
Diagnostic utility of CMR (% of patients for whom CMR identified the cause of stable troponin elevation)
Methodological detailsconsecutive patients, registry database, prospective follow-up
  • Consecutive patients
  • Registry database
  • Prospective follow-up

Main finding

As reported in the abstract

CMR identified cause of stable troponin elevation

Cause identified by CMR

160

71%

Normal CMR

17%

Inconclusive CMR

12%

Observational data: associations, not effects.

Secondary outcomes

Incremental value of CMR

CMR changed referral diagnosis
59 (26%)
Net reclassification index vs pre-CMR referral diagnosis model
0.11
Integrated discriminatory improvement index
0.33

MACE (all-cause mortality and CV readmissions) · median follow-up 4.3 years (IQR 2.8-6.3)

Patients with MACE
72 (32%)

Original publication

Utility of cardiovascular magnetic resonance in patients with stable troponin elevation. Eur Heart J Cardiovasc Imaging. Published 7 November 2022. doi:10.1093/ehjci/jeac215

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