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JACC
Latest from JACC
J Am Coll Cardiol
Natriuretic Peptide Receptor-1 Agonist for Resistant Hypertension: A Randomized Phase 2 Trial
Randomised controlled trialHypertension
J Am Coll Cardiol
Blood Pressure Levels and Outcomes in Type 2 Diabetes: Dose-Response Meta-Analysis of 5.87 Million Cohort Participants
Meta-analysisCardiometabolic & kidney
J Am Coll Cardiol
Chlorhexidine vs Povidone-Iodine Alcohol Solutions for Cardiac Implantable Electronic Devices: A Prospective Randomized Study
Randomised controlled trialArrhythmias & EP
J Am Coll Cardiol
J Am Coll Cardiol
Menopausal Status Associated With Docetaxel-Induced Vascular Dysfunction in Breast Cancer Patients
Mechanistic studyCardio-oncology & other
J Am Coll Cardiol
Underutilized Potential of a Nationwide Community First Responder System
Cohort studyAcute care & resuscitation
J Am Coll Cardiol
Echocardiographic Diastolic Function Grading in HFpEF: Testing the Updated 2025 ASE Criteria
Diagnostic or prognostic studyHeart failure
J Am Coll Cardiol
Heart Failure Quality of Care Among Asian Patients in the United States
Cohort studyHeart failure
J Am Coll Cardiol
Cardiovascular Statistics in the United States, 2026: JACC Stats
Cohort studyPrevention & lipids
J Am Coll Cardiol
J Am Coll Cardiol
J Am Coll Cardiol
Delayed Diagnosis of Transthyretin Amyloid Cardiomyopathy in the Veterans Health Administration
Cohort studyHeart failure
J Am Coll Cardiol
Management of Peripheral Artery Disease in Adults With Diabetes: 2025 ACC Scientific Statement: A Report of the American College of Cardiology
Guideline or statementAortic & peripheral
J Am Coll Cardiol
J Am Coll Cardiol
Obesity-Associated Cardiovascular Risk and Benefit From PCSK9 Inhibition: A Prespecified Analysis From FOURIER
Secondary analysisPrevention & lipids
J Am Coll Cardiol
Association of Lp(a) With Cardiovascular Disease and All-Cause Mortality in U.S. Hispanics and Latinos
Cohort studyPrevention & lipids
J Am Coll Cardiol
Lessons Learned From Treating 34 Million People With Hypertension: The Global HEARTS Initiative
Research articleHypertension
J Am Coll Cardiol
J Am Coll Cardiol
Pulsed Field Ablation Using a Novel Biphasic Catheter vs Thermal Ablation for Paroxysmal Atrial Fibrillation: InsightPFA Trial
Randomised controlled trialArrhythmias & EP
J Am Coll Cardiol
J Am Coll Cardiol
Early vs Late Staged PCI After Subintimal Tracking and Re-Entry for Chronic Total Occlusions: A Randomized Trial
Randomised controlled trialCoronary & ACS
J Am Coll Cardiol
Sex Differences in Dilated Cardiomyopathy: Evidence Gaps and Future Directions
Meta-analysisHeart failure
J Am Coll Cardiol
Trends in the Prevalence, Associated Risk Factors, and Health Burden of Heart Failure in the United States, 1988 to 2023
Cross-sectional studyHeart failure
J Am Coll Cardiol
Age and Sex-Specific Percentiles of 30-Year Cardiovascular Disease Risk Based on the PREVENT Equations
Cross-sectional studyPrevention & lipids
J Am Coll Cardiol
HRS/ACC Scientific Statement: Guiding Principles on the Performance of Intracardiac Ablation Procedures in Ambulatory Surgical Centers
Guideline or statementArrhythmias & EP
J Am Coll Cardiol
Behavioral Economics and Medication Adherence for Hypertension: A Randomized Clinical Trial
Randomised controlled trialHypertension
J Am Coll Cardiol
Effect of Aficamten vs Metoprolol on Patient-Reported Health Status in Obstructive Hypertrophic Cardiomyopathy
Secondary analysisHeart failure
J Am Coll Cardiol
Potent P2Y12 Inhibitor Monotherapy vs DAPT After PCI in Patients With and Without STEMI: The NEO-MINDSET Substudy
Secondary analysisCoronary & ACS
J Am Coll Cardiol
1-Year Outcomes of Novel Balloon-Expandable vs Contemporary Transcatheter Heart Valves in Severe Aortic Stenosis: The LANDMARK Trial
Randomised controlled trialValvular & structural
J Am Coll Cardiol
Proactive Management and Treatment of Aortic Stenosis: An International Expert Perspective
Guideline or statementValvular & structural
J Am Coll Cardiol
Sex-Specific Microaxial Flow Pump Use and Outcomes in Infarct-Related Cardiogenic Shock in the DanGer Shock Trial
Secondary analysisAcute care & resuscitation
J Am Coll Cardiol
J Am Coll Cardiol
J Am Coll Cardiol
Using Transmitral Pressure Gradients and Residual Mitral Regurgitation to Optimize Outcome After Transcatheter Edge-to-Edge Repair
Cohort studyValvular & structural
J Am Coll Cardiol
Association of Lipoprotein(a) and Interleukin-6 With Cardiovascular Risk: MESA and UK Biobank
Cohort studyPrevention & lipids
J Am Coll Cardiol
Multicenter Study on the Safety of Pulsed Field Ablation in Over 40,000 Patients: MANIFEST-US
Cohort studyArrhythmias & EP
J Am Coll Cardiol
Follow-Up Lipid Testing and Statin Initiation Among Young Adults in a U.S. Health Care System
Cohort studyPrevention & lipids
J Am Coll Cardiol
Using Artificial Intelligence to Adjudicate Major Adverse Cardiovascular Events in Clinical Trials
Randomised controlled trialHeart failure
J Am Coll Cardiol
Sacubitril-Valsartan vs Enalapril in Heart Failure Due to Chagas Disease: Primary Results of ANSWER-HF Randomized Trial
Randomised controlled trialHeart failure
J Am Coll Cardiol
Predicting Heart Failure From 12-Lead ECGs Using AI: A HeartShare/AMP-HF Pooled Cohort Analysis
Cohort studyHeart failure